What You Need to Know Post-Transplant: Common Nutrient and Herbal Interactions (2024)

What You Need to Know Post-Transplant: Common Nutrient and Herbal Interactions (1)Stacy Crow, Pharm.D

Fruits and vegetables are healthy dietary choices for most people. As common “healthy” staples on many plates, it is easy to forget that certain fruits and vegetables can interact with transplant medications. Some herbal products may also have similar interactions.

Why do certain foods cause interactions?
These interactions are usually due to either the natural ability of the food to activate the body (even in ways that can be similar to medications) or as a result of drug-food interactions with medications. For transplant recipients, the most frequent interactions are those that activate the immune system and those that affect the ability of the drug to enter or exit the blood. As a result, some foods and herbal products are no longer safe to consume after receiving a transplant.

What foods should I avoid after receiving a transplant?
The below fruits and juices may interact with your immunosuppression, causing toxicity. They should be avoided.

  • Grapefruit and grapefruit juice (please note that some citrus-flavored drinks have a grapefruit extract in them, so it is important to check ingredient lists.)
  • Pomegranate and pomegranate juice
  • Seville Oranges (normal oranges are fine in moderation)

Other fruits and vegetables that should be consumed in moderation are grapes, cranberries, tangerines, cauliflower, and broccoli.1

What supplements or herbal products should I avoid after receiving a transplant?
Many supplements and herbal products have drug interactions with your immunosuppression or may increase the risk of toxicity or rejection. Please talk to your transplant doctor or pharmacist before starting

any

new supplements or herbal products.
Some of the more popular herbal products that can have adverse interactions include:2

  • Vitamin C
  • St. John’s Wort
  • Herbal teas: green tea, chamomile, peppermint, dandelion
  • Echinacea
  • Ginseng
  • Feverfew

Living with a transplant requires achieving a balance between having enough of a natural defense system to protect from everyday sicknesses such as a cold or the flu and lowering the immune system enough to protect the transplant from being attacked and rejected by the body. Please talk to your doctor or pharmacist if you have any questions about what foods, medications, or herbal supplements are safe to use after transplant.

  1. Rodríguez-Fragoso L, et.al. Potential risks resulting from fruit/vegetable-drug interactions: effects on drug-metabolizing enzymes and drug transporters. J Food Sci. 2011 May;76(4):R112-24. doi: 10.1111/j.1750-3841.2011.02155.x. Review. PubMed PMID: 22417366.
  2. Moore LW. Food, food components, and botanicals affecting drug metabolism in transplantation. J Ren Nutr. 2013 May;23(3):e71-3. doi: 10.1053/j.jrn.2013.02.002. PubMed PMID: 23611558.
What You Need to Know Post-Transplant: Common Nutrient and Herbal Interactions (2024)

FAQs

What are the nutrition guidelines for post transplant patients? ›

Eat small frequent meals throughout the day and include protein with every meal. Good sources include poultry (chicken and turkey), fish, seafood, red meats and yogurt. Although high in cholesterol, eggs, nuts and dairy products such as milk and cheese are also good sources of protein.

What herbs should I avoid after a kidney transplant? ›

What supplements or herbal products should I avoid after receiving a transplant?
  • Vitamin C.
  • St. John's Wort.
  • Herbal teas: green tea, chamomile, peppermint, dandelion.
  • Echinacea.
  • Ginseng.
  • Feverfew.

What foods should I avoid after a transplant? ›

Foods to avoid after transplant
  • Raw seafood like clams, oysters, sushi and ceviche.
  • Raw, rare or undercooked meat, poultry and fish.
  • Raw or undercooked eggs.
  • Foods containing raw eggs like cookie dough or homemade eggnog.
  • Unpasteurized milk and unpasteurized cheese.
  • Unpasteurized cider.
  • Bean and alfalfa sprouts.
Jul 2, 2018

What are the nutritional management of renal transplant patients? ›

Limit high-calorie foods such as fatty foods, sweets, pastries, and other foods high in fat or sugar. You can help control your calories by eating: Foods high in fiber, such as vegetables and fruits. Lean meat, skinned poultry and fish.

What not to eat or drink after kidney transplant? ›

Transplant drugs can raise your risk for food-borne illness. You can lower your risk by handling food safely*: • Avoid raw and undercooked meats, seafood, and eggs. Avoid unpasteurized dairy products. Always wash fresh fruits and vegetables with cool, running water before eating.

Which food item would be most important to avoid while taking immunosuppressants? ›

Avoid raw or rare meat and fish and uncooked or undercooked eggs. Cook meat until it's well-done. Thoroughly cook eggs (no runny yolks) and avoid foods containing raw eggs such as raw cookie dough or homemade mayonnaise. Avoid unpasteurized beverages, such as fruit juice, milk and raw milk yogurt.

What fruits should transplant patients avoid? ›

Most foods and drinks are completely safe for you to take after transplant. Please AVOID grapefruit, pomegranate, pomelo, blood orange, and black licorice, as these can increase the amount of anti- rejection medication in your body and this could harm you.

What not to eat when taking tacrolimus? ›

Does tacrolimus interact with any foods or beverages? Avoid excessive intake of high potassium foods (bananas, oranges, orange juice, potatoes, spinach, etc). Do not eat grapefruits, grapefruit juice or any soda (Fresca) or fruit juice blend that contains grapefruit juice.

What herbs interfere with tacrolimus? ›

With regard to patients on immunosuppressive therapy such as tacrolimus and cyclosporine A, herbal products such as turmeric and chamomile are likely to affect these medications, which both have narrow therapeutic indices.

What is the hardest transplant to recover from? ›

“A lung transplant is second only to an intestinal transplant for having some of the most complicated outcomes,” says Jason Turowski, MD, Brian's pulmonologist. “We will find a way to solve what many others say is not solvable.”

Can transplant patients eat ice cream? ›

Limit high sugar foods and drinks. Avoid high calorie foods with low nutritional value such as doughnuts, candy, cookies, ice cream, and other junk food.

Can transplant patients eat peanut butter? ›

high-protein, high-calorie foods to speed healing of the sores such as peanut butter, pasteurized cottage cheese or yogurt. a liquid or blenderized diet, or a complete nutrition supplement such as Ensure®, Boost® or Carnation® Instant Breakfast.

What protein is good for kidney transplant patients? ›

You need more protein to help with healing after transplant surgery. Healing usually takes between 6-8 weeks. Good sources of protein include fish, poultry, egg whites, egg substitutes, lean meat, and low fat dairy (milk, yogurt and cottage cheese).

Can kidney transplant patients drink protein shakes? ›

There is no longer a restriction on potassium, phosphorus, protein or dairy intake after a transplant. This applies to patients who were on a protein-restricted diet before the transplant as well.

What vitamin is deficient in renal transplant? ›

Low vitamin D levels or "vitamin D deficiency" is defined as a total vitamin D level less than 20 ng/mL. This is very common after transplantation. Why is that? In an effort to prevent skin cancer, transplant recipients are advised to avoid or protect themselves from the sun – the body's major source of vitamin D.

What foods should you avoid when taking tacrolimus? ›

Does tacrolimus interact with any foods or beverages? Avoid excessive intake of high potassium foods (bananas, oranges, orange juice, potatoes, spinach, etc). Do not eat grapefruits, grapefruit juice or any soda (Fresca) or fruit juice blend that contains grapefruit juice.

What foods should you avoid after a stem cell transplant? ›

Foods to avoid (unsafe):
  • Unpasteurized and raw milk cheese.
  • Cheeses with molds (e.g., Blue, Gorgonzola, Roquefort, and Stilton cheeses)
  • Soft cheeses (e.g., Brie, Camembert, Feta, Farmer's cheese)
  • Mexican-style cheeses, such as queso fresco and queso Blanco.
  • Sliced cheeses from the deli.

What dietary advice should be avoided by given to patients who have undergone organ transplantation and are taking ciclosporin? ›

Some foods such as grapefruit are best avoided by patients taking ciclosporin as it may alter the drug's metabolism, meaning the drug's actions become unpredictable. You may wish to ask you doctor or nurse for advice about this.

How much protein should a kidney transplant patient eat a day? ›

Once you leave the hospital and your steroid dose decreases, your protein needs will go down to 1.2 to 1.5 grams of protein per kilogram of body. Then longer term, a few months to years after transplant, your protein needs are about 1 gram per kilogram of body weight.

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