Method comparison measures the closeness of agreement between the measured values of two methods.
Note: The term method is used as a generic term and can include different measurement procedures, measurement systems, laboratories, or any other variable that you want to if there are differences between measurements.
- Correlation coefficient
A correlation coefficient measures the association between two methods. - Scatter plot
A scatter plot shows the relationship between two methods. - Fit Y on X
Regression of Y on X describes the linear relationship between the methods. - Linearity
Linearity is the assumption that the relationship between the methods is linear. - Residual plot
A residual plot shows the difference between the measured values and the predicted values against the true values. - Average bias
Bias is a measure of a systematic measurement error, the component of measurement error that remains constant in replicate measurements on the same item. When measuring a method against a reference method using many items the average bias is an estimate of bias that is averaged over all the items. - Difference plot (Bland-Altman plot)
A difference plot shows the differences in measurements between two methods, and any relationship between the differences and true values. - Fit differences
Regression of the differences on the true value describes the relationship between the methods. - Limits of agreement (LoA)
Limits of agreement estimate the interval within which a proportion of the differences between measurements lie. - Mountain plot (folded CDF plot)
A mountain plot shows the distribution of the differences between two methods. It is a complementary plot to the difference plot. - Agreement measures for binary and semi-quantitative data
Agreement measures summarize the similarity of the results of two binary or semi-quantitative methods. - Agreement plot
An agreement plot shows the agreement between two binary or semi-quantitative methods.
Available in Analyse-it Editions
Method Validation edition
Ultimate edition