Method comparison / Agreement > Statistical Reference Guide (2024)

Method comparison measures the closeness of agreement between the measured values of two methods.

Note: The term method is used as a generic term and can include different measurement procedures, measurement systems, laboratories, or any other variable that you want to if there are differences between measurements.

  • Correlation coefficient
    A correlation coefficient measures the association between two methods.
  • Scatter plot
    A scatter plot shows the relationship between two methods.
  • Fit Y on X
    Regression of Y on X describes the linear relationship between the methods.
  • Linearity
    Linearity is the assumption that the relationship between the methods is linear.
  • Residual plot
    A residual plot shows the difference between the measured values and the predicted values against the true values.
  • Average bias
    Bias is a measure of a systematic measurement error, the component of measurement error that remains constant in replicate measurements on the same item. When measuring a method against a reference method using many items the average bias is an estimate of bias that is averaged over all the items.
  • Difference plot (Bland-Altman plot)
    A difference plot shows the differences in measurements between two methods, and any relationship between the differences and true values.
  • Fit differences
    Regression of the differences on the true value describes the relationship between the methods.
  • Limits of agreement (LoA)
    Limits of agreement estimate the interval within which a proportion of the differences between measurements lie.
  • Mountain plot (folded CDF plot)
    A mountain plot shows the distribution of the differences between two methods. It is a complementary plot to the difference plot.
  • Agreement measures for binary and semi-quantitative data
    Agreement measures summarize the similarity of the results of two binary or semi-quantitative methods.
  • Agreement plot
    An agreement plot shows the agreement between two binary or semi-quantitative methods.

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Method comparison / Agreement  > Statistical Reference Guide (2024)
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